Fredericktown is a city in and the county seat of Madison County, Missouri, United States, in the northeastern foothills of the St. Francois Mountains. The population was 3,985 at the 2010 census. The city is surrounded on three sides (east, west, and south) by the easternmost parcel of the Mark Twain National Forest.
Farmington is a city in St. Francois County located 72 miles (116 km) southwest of St. Louis in the Lead Belt region in Missouri in the United States. As of the 2010 census, the population was 16,240. It is the county seat of St. Francois County. Farmington was established in 1822 as Murphy's Settlement, named for William Murphy of Kentucky who first visited the site in 1798. When St. Francois County was organized, the town was briefly called St. Francois Court House and later renamed to Farmington.
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